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Global Seed Industry - DS254
Published October 2006

Reports 2006

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CHAPTER 1 - INTRODUCTION

It can be argued that plant breeding has played and will continue to play as important a role in the progress of civilisation as any technology. It was the selection of plants with the best seed yields that enabled the early farmers to develop and so provide food for towns and non-farming inhabitants. Our global population is expected to increase to eight billion by 2025 with little possibility of access to further suitable land for farming except in South America. Current prime land is being lost to housing and industry. Our food supply will have to be produced from an ever-smaller area so that productivity per unit area will have to increase significantly. It is fortunate that technology has made huge strides in recent years so that there seems to be little doubt that both the quantity and quality of food and animal feed can be increased to meet the challenge.

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All the large seed companies and organisations involved in plant breeding have been embracing the tools of modern technology that are facilitating the advances being made in plant breeding. Truly, the Age of Chemistry is giving way to the Age of Biology, where plants are seen as not only being able to provide food and feed but also the raw material for energy generation – ethanol and biodiesel – raw materials for plastics, improved fibres and vaccines. Chapter 5 will touch on some of the technologies, such as genomics, molecular markers, bioinformatics and genetic engineering, that are facilitating and speeding up the breeding process.

Large multinational plant science companies have collaborated with leading-edge biotech boutique companies and organisations, in moves that have allowed seed companies to take advantage of technology in genomics, gene modification and other areas being developed in the field of human health. While traditional plant breeding could undoubtedly have continued to provide yield increases, further significant increases require the application of more fundamental science.

Clearly, the higher cost and sophistication of modern technology for plant breeding makes it more difficult for smaller companies to survive and favours the larger multinational companies.

Environmentalists are critical of genetic modification and the planting of hybrids and introduced varieties. Yet, all our major world crops spread around the world over many thousands of years, thereby becoming adapted to a much wider range of climatic and soil environments than those of their place of origin. The precision of modern genetic modification and understanding of genomics will speed up this process and provide plants that serve us and the environment in the most sustainable way.

The seed industry needs appropriate safeguards for its intellectual property rights, since the very nature of seed allows reproduction. The World Trade Organization’s (WTO) 1994 agreement on Trade-Related Aspects of Intellectual Property Rights (TRIPS) requires that countries either adopt the plant variety protection (PVP) system of Geneva-based intergovernmental organisation the International Union for the Protection of New Varieties of Plants (UPOV), or initiate plant patenting, or both. More and more countries are joining UPOV (59 to date) and other countries have some local form of PVP, but an appropriate infrastructure and will to carry out enforcement is essential. This topic will be addressed in more detail in the final chapter.

A much wider range of seed treatments has been introduced, offering greater protection from both soil and early foliar insects and diseases. Chapter 6 can only offer a brief overview of this subject, but a new Agrow report under preparation will provide a complete review and details.

1.2 Seed Industry – company acquisitions

Anyone following the progress of the global seed industry will be aware of the significant changes that have occurred since the last Agrow report covering this sector (Global Seed Markets, DS208, October 2000). The major plant science companies have been consolidating their position through further acquisitions and technology investments. The International Seed Federation (ISF) Secretary General estimated at the Santiago Chile 2005 World Seed Congress that consolidation in the seed industry, as measured by the top five companies, has increased from 8% to 25% over the past 20 years (A Dansby, 2005).

The acceptance of GM traits in North America for use in soybeans, corn, cotton and canola has focused attention on these crops. Vegetable consumption has increased throughout the world as developed countries have recognised the importance of good nutrition and developing countries have improved their standards of living. By contrast, the early attention paid to wheat by Monsanto and DuPont/Pioneer, in particular, has waned. Hybrid rice and cotton in Asia (pioneered in India) may provide the incentive for acquisitions and consolidation in these still largely undeveloped markets.

Crop protection chemicals continue to ring the cash register, but competition has become fierce. Monsanto is already getting more revenue from seeds and traits than from its agrichemical business. Syngenta forecasts that seeds will contribute 40% of its total sales in the future, increasing from around 20% at present. In 2004 Pioneer contributed 42% of the revenue of DuPont’s agricultural businesses versus 36% for crop protection chemicals. Bayer has been divesting its corn seed businesses (Pau Seeds in the US and its seed subsidiary in Argentina), but focusing on vegetables (Nunhems), cotton (Fibermax), rice and canola. Dow AgroSciences is focusing on corn, sunflowers, other field crops and cotton (Phytogen in the US). All these major international companies have invested heavily in new technology.

There have also been some examples of companies building up significant seed industry assets and then disintegrating, such as AgriBiotech in the US, while Advanta was the result of a merger of seed interests.

Recent acquisitions have often been intended to build critical mass in major markets, such as the US corn market. Many of the large companies have also been investing in Asia, particularly India and China, or have had Asian subsidiaries for several years.

There are indications that the generic agrichemical companies are interested in investing in seed companies. United Phosphorus entered the global seed business with its purchase from Fox Paine of the remaining Advanta global seed businesses. Nufarm has also acquired some regional seed companies in its home base, Australia. Acquisition of a fast-growing hybrid seed company in China may presage more privatisation and consolidation. Clearly, seeds are seen to be a growth opportunity, with the potential to provide more integrated production inputs for farmers and growers.

1.2.1 Monsanto

Monsanto became the market leader in 2005 with the acquisition of Seminis, which lifted the group’s share of the global vegetable seeds market to an estimated 20%. In its field crops businesses the group has been pursuing a strategy of acquiring market share in US corn and soybeans by purchasing regional seed companies through its holding company, American Seeds Inc (ASI). This complements the organic growth it expects to get via improvements in its hybrids achieved within the 12 corn breeding programmes it has acquired. Channel Bio has become the parent company under ASI for the regional seed companies such as Midwest Genetics, Inc and Wilson Seeds.

Some of the main acquisitions are shown in Table 1.1.

Table 1.1: Major acquisitions by the Monsanto group

Acquiring company

Company acquired

Date acquired

Price US
$ million

Details

Monsanto

Limagrain Canada Seeds

July 2001

-

Acquires canola germplasm, breeding programme and licence agreements.

Monsanto/ASI

Channel Bio, US

November2004

120

Channel Bio has 2% of US corn market with its three seed brands.

Monsanto

Advanta Seeds, Canada

November 2004

-

Canola seed.

Monsanto

Seminis Inc

January 2005

1,400

Seminis is the largest vegetable and flower seed company with a 20% market share.

Monsanto/ASI

NC + Hybrids

March 2005

40

NC has around 1% of US corn market. Will operate as subsidiary of Channel Bio (Indiana).

Monsanto/ASI

CORE Group (Five US regional seed companies)

2005

52

Expands Monsanto’s geographic coverage of US corn markets (CORE Group has around 1% of the market).

Monsanto

Emergent Genetics

2005

300

Emergent Genetics has 12% of the US cotton seed market and is also in India. Emergent and NexGen brands. 2004 sales US$68.9 million.

Monsanto/ASI

Gold Country Seed, Minnesota, US Heritage Seeds, Indiana, US

March 2006

8.7

Expands Monsanto’s geographic coverage of corn market (these companies have 0.4% of US corn market).


1.2.2 DuPont/Pioneer Hi-Bred

The only significant acquisition or investment by DuPont Pioneer has been of a technology company, Verdia, based in Redwood City, California. Verdia was purchased from Maxygen.

Table 1.2: Acquisitions by DuPont/Pioneer Hi-Bred

Acquiring company

Company acquired

Date acquired

Price US
$ million

Details

DuPont /Pioneer Hi-Bred

Verdia, Inc (biotechnology)

July 2004

64

Acquired from Maxygen.


1.2.3 Syngenta

Syngenta has made a number of acquisitions to build on its Northrup King field crops business in the US, with the aim of gaining access to technology and expanding its global reach in vegetables and flowers. The acquisitions were concentrated in 2004, as shown in Table 1.3.

Table 1.3: Syngenta’s acquisitions

Acquiring company

Company acquired

Date acquired

Price US$ million

Details

Syngenta

Dia-Engei, Japan

February 2004

-

Acquired Japanese leader in flower and vegetable seedlings. Sales of US$8 million in 2003.

Syngenta

CHS Research LLC

February 2004

-

Acquisition of certain corn breeding material and research collaboration.

Syngenta

Golden Harvest group

June 2004

180

90% share gives 4% of US corn and 3% soybean markets.

Syngenta

Advanta BV (North American Maize and soybean business)

May 2004

297
(€239)

Garst brand corn and soybeans in N. America giving Syngenta 10% corn share in the US.

Syngenta

Purchased from Bayer CropScience

May 2004

 

GA21 glyphosate tolerance gene technology.


1.2.4 Dow AgroSciences

Dow AgroSciences has acquired a number of seed companies, particularly in the US and Brazil. Its market share in the US, through Mycogen Seeds – acquired fully in 1998 – was boosted by the acquisition of the North American field seeds business of Cargill Hybrid Seeds in 2000. In the same year, Empresa Brasilieira de Sementes of São Paulo was added to its existing companies in Brazil – Hibridos Colorado, FT Biogenetica, Hibridos Hata and Dinamilho. Cotton also became a focus through its joint venture with the JG Boswell company Phytogen.

Table 1.4: Acquisitions by Dow AgroSciences

Acquiring company

Company acquired

Date acquired

Price US$ million

Details

Mycogen Seeds (Dow AgroScience)

Cargill Hybrid Seeds

October 2000

-

Acquires Cargill’s North American seed business – corn, soybeans, sunflower, alfalfa and sorghum.

Dow AgroSciences

Empresa Brasileira de Sementes (EBS), São Paulo, Brazil

August 2000

 

Gains EBS’ maize and sorghum business to add to Dow’s other Brazilian seed businesses.


1.2.5 Bayer

Bayer BioScience is the business group based in Lyon, France, responsible for the company’s seed and biotechnology involvement. Bayer has divested its corn seed companies in the US and Argentina and has acquired further capacity to handle the increasing seed business of its successful US FiberMax seed company. The holding company for all Bayer’s vegetable seed companies was changed from Nunza to Nunhems in July 2005 and operates in 20 countries from its original base in the Netherlands. The acquisition of Icon Genetics AG in Germany indicates Bayer’s determination to use plants to produce pharmaceuticals, an important business for Bayer.

Table 1.5: Acquisitions and divestments by Bayer

Acquiring company

Company acquired

Date acquired

Price US$ million

Details

Bayer

Pau Seeds Inc, Iowa, US

2002

-

Controlling interest in four active corn breeding programmes.

Pannar

Pau Seeds (Bayer)

2005

-

Acquires corn seed company from Bayer.

Bayer

Associated Farmers Delinting Inc, Texas

2005

11.4 ( €9 million)

Regional seed company with local storage and processing facilities.


1.2.6 BASF

BASF is not listed in the 20 companies featured in Chapter 3, nevertheless it has made some strategic acquisitions in the seed industry. In 1998, BASF acquired 40% of the Swedish company Svalőf Weibull, with its strong cereals and field crops seed business, geared to supplying the needs of farms in northern climates. Thurston Genetics in the US was acquired in 2000 and BASF/Thurston Inc is constructing a building for its R&D staff next to BASF Plant Science Research facility in Minnesota. In December 2005, BASF obtained exclusive licensing rights to genetic traits discovered by Belgium’s CropDesign for use in major crops and a multi-year research co-operation agreement. BASF is also planning to grow genetically modified potatoes resistant to potato blight.

In addition to investments in seed companies, BASF has been funding research to introduce tolerance to imidazolinone herbicides in germplasm of major field crops via its Clearfield system which relies on conventional breeding technology. This has involved both public sector organisations and private seed companies involved in rice, wheat, sunflowers, canola and so on.

Table 1.6: Acquisitions by BASF

Acquiring company

Company acquired

Date acquired

Price US$ million

Details

BASF

ExSeed Genetics, Kentucky, US

December 2000

-

Acquired corn biotechnology and genetics company – NutriDense brands


BASF is also involved in two joint ventures with two plant biotechnology companies based in Germany. The Sungene venture centres on the discovery of genes with the aim of producing valuable traits in genetically optimised plants. Metanomics also concentrates on understanding gene function so that genes of agricultural interest, such as enhanced nutrition and climatic stress, can be found.

1.2.7 Other companies

There have been some significant acquisitions by other major players such as Florimond Desprez, Limagrain and RAGT, increasing their involvement in the US market. KWS has also increased its investment in the US and acquired the remaining share of CPBTwyford .The South African group Pannar has been extending its overseas interests with the purchase of Bayer’s Pau Seeds in the US. In China, the seed industry continues to evolve. Chardan China Acquisition Corp has purchased Origin Seed Technology Inc, which in the six years since it was founded has become the seventh fastest-growing company in mainland China, according to Deloitte Touche Tohmatusu’s list. The company has specialised in hybrid seeds, initially corn, but latterly cotton and hybrid rice.

These and other selected acquisitions in the seed industry are shown in Table 1.7.

Table 1.7: Acquisitions by various companies

Acquiring company

Company acquired

Date acquired

Price US$ million

Details

Chardan China Acquisition Corp

Origin Agritech Seed Technology, Inc

2005/2006

-

Acquisition of one of the largest and fastest-growing hybrid seed companies in China.

DLF-Trifolium AS

Cebeco Seeds Group

January 2003

-

Acquired Cebeco’s grains and flax businesses.

Florimond Desprez

Seedex Inc, Colorado, US

2000

-

Acquired sugar beet, corn and other seeds business.

Fox Paine

Advanta’s worldwide seed business +

September 2004

-

Acquired from Syngenta. All operations outside North America + non-corn/soybean business in North America.

Grainco, Australia

Elders, Australia

 

-

Merger to form PlantTech Pty Ltd, with combined field crop and pasture seed businesses.

J.C.Robinson Seeds

Zelder, Netherlands

2003

-

Maize breeding, production and marketing.

J.R.Simplot

AgriBiotech’s turfgrass business

2000

-

Acquisition of the US- based turfgrass breeding and production business.

KWS (AgReliant)

Producers Hybrids, Nebraska, US

2005

-

Acquires corn, soybeans, alfalfa and other filed crop seeds business in western US.

KWS

CPBTwyford

July 2005

-

Purchases remaining 26% share.


Land O’Lakes, Minnesota

Hytest Seeds

2000

-

Acquires AgriBiotech’s US business in corn, soybeans, sorghum, wheat and other forages.

Limagrain

Advanta’s European seed businesses

December 2004

-

Range of field crop seed businesses and two US business units.

Nidera, NL

Bayer Argentine subsidiary

May 2005

-

Bayer’s soybean and maize research and processing will now be Nidera Seeds.

Pannar

Pau Seeds (Bayer)

2005

-

Acquires corn seed company from Bayer.

PlantTech, Australia

SGB Australia

2002

-

Purchases seed division from Wesfarmers Landmark.

RAGT Genetique SA

Plant Breeding International Cambridge

April 2004

25

Monsanto’s European wheat and barley seed business.

Sakata Seed

Alf Christianson, US

April 2002

-

Completed purchase of seed company.

Sakata Seed

Daehnfeldt A/S

August 2003

-

Acquired flower seeds division.

Sakata Seed

Qualiveg

2005

-

Access to cucurbit breeding lines.

Stine Seed Company, Iowa

ProdiGene Inc.

 

-

Gained ownership of research company in biopharm crops.

Svalőf Weibull AB, Sweden

Danisco winter oilseed rape

May 2004

-

Acquires winter oilseed rape breeding programme.

United Phosphorus, India

Fox Paine’s Advanta seed businesses

2005

-

UP acquired the Advanta seed businesses in Latin America and Australia from Fox Paine.


The last few years have seen the break up of Advanta, a company established by AstraZeneca and Royal Cosun. First, Limagrain purchased the field crop business and then, in May 2004, Syngenta acquired the remaining part of Advanta BV. Syngenta retained the North American corn and soybeans business plus AgriPro Wheat and sold the rest of Advanta’s worldwide business to Fox Paine & Co, a US-based private equity firm. Fox Paine also took a 10% share in the North American business formerly acquired by Syngenta. In November 2004, Monsanto acquired the North American canola assets of Advanta Seeds in Canada. In 2005, Florimond Desprez bought the sugar beet seed business. In 2006, United Phosphorus acquired the international Advanta companies previously purchased by Fox Paine.

The US company AgriBiotech, based in Nevada, acquired many seed companies covering several different crops during the 1980s, but this company has also been broken up.

1.2.8 New entrants

Two recent developments indicate that major international generic agrochemical companies are taking steps to enter the seed industry.

Nufarm acquired the Australian-based canola seed breeder, Agseed Research, in 2004 and, then, in November 2005 completed the buyout of two partners in Nugrain, another Australian plant breeding alliance it had set up in 1998. In December 2005, Nugrain purchased a 50% stake in Access Genetics from its founder.

Nufarm management sees synergy in being able to deliver biology as well as chemicals. Nufarm now has global sales of US$1.6 billion after four years of double-digit growth, and it may bring the same drive and energy to the seed industry.

United Phosphorus has acquired Advanta Netherlands Holdings from Fox Paine, the US investment group. Advanta Netherlands had sales of US$73 million in 2005. Advanta’s operations involved Australia (Pacifica), Asia (Pacific Seeds Thailand and Advanta India) and Latin America (Advanta Semillas and Sunsat in Argentina, and a joint venture in Chile, Compania Internacional de Semillas). United Phosphorus will acquire these operations and the research and development programmes in rice, maize, sunflowers, sorghum and canola.
United Phosphorus has been growing its agrochemical business and will be able to promote its seed treatments through these seed companies.

1.3 Licensing companies

Licensing has enabled Monsanto to include its Insect Resistant (IR) and Herbicide Tolerant (HT) traits not only in the germplasm of its own seed brands, but also in the hybrids and varieties of any company willing to agree to the licensing agreement. As a result, Monsanto claims that its traits are used in 89% of the global acreage devoted to GM crops.
Monsanto has two licensing companies – Corn States for corn and Cotton States for cotton. Dow AgroSciences has a licensing company to license its own germplasm and traits, and this is also able to act for other technology and germplasm owners.

In April 2006, Syngenta Seeds, Inc and DuPont subsidiary Pioneer announced the seed industry’s first 50:50 joint venture to out-license genetics to US and Canadian seed companies, with potential to expand worldwide. Greenleaf Genetics LLC, set up by Syngenta in 2004, will be the licensing organisation. The two companies also agreed to cross-license certain corn and soybean traits that each will market independently under its own seed brands. The agreement includes rights for Syngenta to market the new Optimum™ GAT™ herbicide-tolerant trait developed by Pioneer.

This licensing and cross-licensing has made it possible for seed companies to gain access to a range of transgenic traits. The Independent Professional Seedsmen Association, which acts on behalf of independent seed companies in the US, was quick to praise the Syngenta/DuPont decision, saying that it would enhance its ability to distribute products that bring the ultimate in performance and profitability to growers in the organisation’s market area.

Clearly, the broad licensing of traits has enabled many smaller seed companies to access the latest traits and improved germplasm, and so enhance the quality of their products and services in their local market and compete more effectively.

1.4 Licensing agreements


With the recent explosion in seed breeding technology, it has become clear that seed companies will not be able to develop in-house expertise in all the new areas of biotechnology. Over the past few years, most of the large multinational companies have acquired companies with special biotechnology expertise or have initiated research and commercial licensing agreements. Some of the collaborations have involved significant funding, others a collaboration between public institutions and industry.

The US$50 million agreement between Dow AgroSciences and Sangamo Biosciences Inc in California, is considered to be one of the largest plant research collaborations in recent years. Sangamo will provide its proprietary zinc finger protein (ZFP) DNA-binding technology on an exclusive basis for Dow to use in plants to develop new agricultural and industrial products, on a non-exclusive basis, for the animal health and biopharmaceutical markets. Dow AgroSciences is also collaborating with the University of Melbourne to pursue development of plant-made production systems for an avian influenza vaccine.

1.5 Foundation seed companies

There are an estimated 265 smaller regional seed companies in the US (Hagen, 2005), whose survival has been promoted by foundation seed companies and brokers. The largest commercial corn foundation seed company, Holdens, was purchased by Monsanto in 1998 but continues to provide hybrids and inbreds for private labelling to many seed firms, while several other companies supply corn hybrids for private labelling and inbreds for use in breeding programmes.

Stine Seed Company is another example of a major company that supplies many companies with inbreds, hybrids and varieties. It claims to have the industry’s largest soybean breeding and development programme and develops and tests nearly one million unique varieties each year. Stine supplies soybean varieties to many seed companies, and claims that its soybean genetics are among the most widely planted in the US. It also has a major corn breeding programme and tests more than 100,000 different preliminary hybrids annually. The company has been successful in its breeding programmes and has been able to supply the needs of many firms that lack the resources to breed and produce varieties and corn hybrids of their own.

1.6 New markets

1.6.1 Input traits

There has always been a strong relationship between crop varieties and crop protection, because of varietal variation in susceptibility, resistance or tolerance to diseases, insect pests and herbicides. The introduction of specific transgenic or conventional traits has allowed the control of specific insect groups and the use of herbicides which otherwise would have damaged if not killed the crop completely. Clearly, this new market has developed over the last ten years and has largely driven market share gains in those countries where the crops have been permitted and marketing has been possible. This segment now embraces 90 million ha worldwide and 8.5 million farmers in 21 countries.

BASF’s Clearfield system has allowed the use of selected imidazolinone herbicides in a range of crops through conventional breeding, so avoiding the problems of GM crops. This has created another new defined market segment.

Several companies are working on disease resistance to such important pathogens as potato blight (Phytophthora infestans) so that a new market segment will be established that adds value to seed by reducing or precluding the need to spray with fungicides.
Farmers, at least in the US, are anxious to facilitate their crop management by purchasing stacked traits, combining both weed and insect control traits. This may obviate the need to apply insecticides and allow use of a total herbicide, such as glyphosate or glufosinate, or a herbicide combination.

1.6.2 End-user or output traits

End-user traits – providing crops and products of value to the processor and end-user – have long been touted as he big breakthrough in biotechnology. Availability of more healthy oils and nutritious vegetables would make consumers look more favourably on GM crops and help them to become comfortable with the technology. The specialty canola oils and VISTIVE soybeans, familiar in the US, are now starting to be grown in large areas in Canada. This topic will be explored further in Chapter 8.

The USDA APHIS website indicates that many field crops are under development for a variety of end-user traits. There has so far been reluctance to invest in vegetables and fruit, because of concerns about consumer acceptance and high costs relative to the size of the market opportunity. Activity may increase once the consumer becomes more comfortable with GM crops and if the final product can indeed command a premium to cover development and marketing costs.

There is increasing pressure to have strict identity preservation, so that food and feed constituents can be traced back to the field/farm where the crop was grown. A reliable and cost-efficient system will be critical, to ensure separation of value-added grain and produce through the supply chain.

1.6.3 Organic crops

There has been a strong trend in Europe, the US, Japan and other countries for upscale purchasers to buy organic produce, food and livestock products. Legislation is not consistent between countries regarding the requirement for organic seed to be used in organic production. Some countries indicate that organic seed should be used if available locally, but if it’s only conventional seed that is obtainable the crop can still be labelled organic. In the EU, there are three categories of crops grown organically for which derogation is allowed so that conventional seed may be used. Certified organic seed, particularly seed of high quality, may be difficult if not impossible to obtain in many parts of the world.

Producing high-quality seed without the use of chemicals is challenging and few effective organic materials can be used for seed treatment. Seed priming may be particularly important for organic seeds, to ensure rapid and even germination, with the aim of producing vigorous and healthy seedlings, and to help the plants compete with weeds.

It is estimated that around ten companies in the world produce organic seeds (Priel, 2005) but there are probably a greater number operating on the local level. Organic production has been levelling off in Europe, but the market is still growing at 20% per year in the US. Organic producers are usually a mixture of large-scale producers and several small local operations. It will be a challenge to produce the variety of seed required for both local markets and the larger national producers and exporters.

If organic production continues to increase, more niche market opportunities will appear for high quality organic seed.


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