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spacerAgrow Reports
Agrow’s Complete Guide to Generic Pesticides: Volume 2
Products and Markets - DS250
Published 1 August 2005

Reports 2005

> Not a subscriber? Subscribe to Agrow to receive the full report

CHAPTER 1 - OVERVIEW


1.1 Background to reports

Generic pesticides and the companies that produce them are becoming an increasingly important part of the agrochemical industry. A combination of the general decline in the discovery of new pesticide active ingredients (ais) and the steady loss of patent protection on existing ais means that the generic pesticide industry is growing faster than the R&D-based agrochemical industry.

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This growth is in terms of both numbers of available ais and total sales. There are no authoritative figures available for the size of the generic pesticide industry, but in 1996 it was estimated to account for around 10% of the global agrochemical industry. In 2005, it is likely to account for 20–30% of the global agrochemical industry, which means that it now generates annual sales of $6,000–$9,000 million.

This report is the second in a set of three investigating the current state of the generic pesticide industry and market. The first report contains profiles of 100 of the most important generic pesticide companies in the world today. This second report contains profiles of 100 of the most important generic pesticide ais. The third report provides a detailed analysis of the generic pesticide market and industry, and explores the forces that will drive the development of the generic pesticide industry over the next few years. These three reports are updated editions of similar reports on the generic pesticide industry that Agrow published first in 1998 and then, as a new edition, in 2001.

In these current reports, a generic pesticide company is defined as a company, or division of a company, that undertakes as part of its business the manufacture of pesticide ais for which the patents have expired. For the first time in this set of reports, the author has not excluded companies that held the original patents to those ais, which means that Monsanto is now a profiled company.

1.2 Outline of Companies report

The 100 companies that are profiled in the first report are listed in Table 1.1. In deciding which specific generic pesticide companies to profile, the main criteria used was generic pesticide sales, and for the top 50 companies this proved to be the only necessary criteria.

However, the generic pesticide industry is made up of only a relatively few companies with annual sales over $100 million, and hundreds of smaller companies with sales under $100 million (most of which have sales below $20 million). Deciding which of these companies to profile proved much more difficult, especially as sales figures for many of these companies were unavailable. The author chose the bottom 50 companies based mainly on the quality and quantity of information available. Information was obtained from company web sites and from stories that have appeared in Agrow. Nevertheless, the profiled companies provide an accurate picture of the current state of the generic pesticide industry.

Table 1.1: List of profiled generic pesticide companies

Company name

Country1

Company name

Country1

AgriGuard

Ireland

Jiangsu Yangnong

China

Agripec

Brazil

Jiangsu Yinka Chemical

China

Agro-Chemie

Hungary

Jingma Chemicals

China

AgroDragon

China

Kangmei Chemical

China

Agro-San

Turkey

Kenso Corp

Malaysia

AH Marks

UK

Koruma

Turkey

Aimco Pesticides

India

Kuaida Agrochemical

China

Albaugh

US

Lanxi Agrochemical

China

Amvac

US

LG Life Sciences

South Korea

Ancom

Malaysia

Luxembourg Industries

Israel

Atabay

Turkey

Makhteshim

Israel

Atul

India

Meghmani Organics

India

Barclay Chemicals

Ireland

Monsanto

US

Bharat Group

India

Nagarjuna

India

Bilag Industries

India

Newsmart Chem-Spec

China

CAC

China

Nitrokemia 2000

Hungary

Cequisa

Spain

Nordox

Norway

Cerexagri

US

Nufarm

Australia

Chemet Chemicals

India

Oltchim

Romania

Chemia

Italy

Pilarquim

Taiwan

Cheminova

Denmark

Pinus

Slovenia

CNCCC.JS

China

PT Petrosida Gresik

Indonesia

Coromandel Fertilisers

India

Punjab Chemicals

India

CUCHEM

China

Qinfeng Pesticides

China

Dalian Dyechem

China

Quimica Lucava

Mexico

Dhanuka Pesticides

India

Rallis India

India

Dongbu Fine Chemicals

South Korea

Red Sun

China

Dooyang Industrial

South Korea

Reposo

Argentina

Excel Crop Care

India

Rotam

Hong Kong

Ficom

India

Sabero Organics

India

Fujian Sannong

China

Sanonda

China

Gharda Chemicals

India

Seven Continent

China

Gold Harvest

China

Shandong Vicome Greenland

China

Griffin

US

Shanghai Zhongxi

China

Heben Pesticide

China

Shenzhen Cereals

China

Hektas

Turkey

Sinochem Hebei

China

Henglong Pesticide

China

Sinochem Jiangsu

China

Heranba

India

Sinochem Ningbo

China

Herbex

Portugal

Sinon

Taiwan

Herbos

Croatia

Sipcam-Oxon

Italy

Hikal

India

Suzhou Worldbest

China

Hindustan

India

SWAL Corporation

India

Hui Kwang

Taiwan

Taminco

Belgium

India Pesticides

India

Tekchem

Mexico

Indofil

India

United Phosporus

India

Inquiport

Venezuela

Veterina

Croatia

IpiCi

Italy

Xinyi Pesticide

China

IQV

Spain

Yancheng Huanglong

China

Isagro

Italy

Zagro

Singapore

Jiangsu Baoling Chemical

China

Zibo Nab Agrochemicals

China

Note: 1 Refers to the country where the headquarters of the main pesticide business is based

Each company profile contains contact details for the company, followed by a one paragraph overview of the company and its activities. The profile then consists of: a more detailed description of the company and its background; a figure for its annual pesticide sales; a list of the main generic pesticide ais that it manufactures; details on its manufacturing and R&D facilities; a list of its major joint ventures and agreements with other companies; and a short section on the company’s strategy and outlook. Not all of these sections will appear in every company profile.

1.3 Outline of Products and Markets report

The 100 ais that are profiled in the second report are listed in Table 1.2. The criteria for choosing these included the number of generic companies manufacturing each ai, annual sales and usage figures, and how recently the ai lost its patent protection.

Table 1.2: List of 100 generic pesticide ais

Active ingredient

Activity

Active ingredient

Activity

2,4-D

Herbicide

hexaconazole

Fungicide

abamectin

Insecticide

imazalil

Fungicide

acephate

Insecticide

imazethapyr

Herbicide

acetamiprid

Insecticide

imidacloprid

Insecticide

acetochlor

Herbicide

ioxynil

Herbicide

alachlor

Herbicide

isoproturon

Herbicide

alpha-cypermethrin

Insecticide

lambda-cyhalothrin

Insecticide

ametryn

Herbicide

linuron

Herbicide

amitraz

Insecticide

malathion

Insecticide

anilofos

Herbicide

mancozeb

Fungicide

atrazine

Herbicide

maneb

Fungicide

benomyl

Fungicide

MCPA

Herbicide

bensulfuron-methyl

Herbicide

metalaxyl

Fungicide

bentazone

Herbicide

metamitron

Herbicide

bifenthrin

Insecticide

methamidophos

Insecticide

bromoxynil

Herbicide

methomyl

Insecticide

buprofezin

Insecticide

metolachlor

Herbicide

butachlor

Herbicide

metribuzin

Herbicide

captan

Fungicide

metsulfuron-methyl

Herbicide

carbaryl

Insecticide

molinate

Herbicide

carbendazim

Fungicide

monocrotophos

Insecticide

carbofuran

Insecticide

myclobutanil

Fungicide

carbosulfan

Insecticide

oxyfluorfen

Herbicide

chlormequat chloride

Herbicide

paraquat

Herbicide

chlorothalonil

Fungicide

parathion-methyl

Insecticide

chlorotoluron

Herbicide

PCNB

Fungicide

chlorpyrifos

Insecticide

pendimethalin

Herbicide

chlorsulfuron

Herbicide

permethrin

Insecticide

clomazone

Herbicide

phorate

Insecticide

copper oxychloride

Fungicide

phosphamidon

Insecticide

cyfluthrin

Insecticide

prochloraz

Fungicide

cyhexatin

Insecticide

profenofos

Insecticide

cymoxanil

Fungicide

prometryn

Herbicide

cypermethrin

Insecticide

propamocarb

Fungicide

deltamethrin

Insecticide

propanil

Herbicide

dicamba

Herbicide

propargite

Insecticide

dichlorvos

Insecticide

propiconazole

Fungicide

diclofop-methyl

Herbicide

pyrazosulfuron-ethyl

Herbicide

dicofol

Insecticide

pyridaben

Insecticide

dimethoate

Insecticide

quinalphos

Insecticide

diniconazole

Fungicide

quinclorac

Herbicide

diuron

Herbicide

simazine

Herbicide

endosulfan

Insecticide

tebuconazole

Fungicide

ethion

Insecticide

terbufos

Insecticide

fenthion

Insecticide

thiophanate-methyl

Fungicide

fenvalerate

Insecticide

thiram

Fungicide

fluometuron

Herbicide

triadimefon

Fungicide

fluroxypyr

Herbicide

trichlorfon

Insecticide

fosetyl-aluminium

Fungicide

trifluralin

Herbicide

glyphosate

Herbicide

ziram

Fungicide


Each profile will begin with a box detailing the activity and general uses of that specific ai. The profile will then continue with: details on the generic companies that currently manufacture the ai; information on the registration status of the ai in major markets such as the US and EU; and information on the size of the global market.

1.3 Outline of Business Strategies report

The third report contains an analysis of the generic pesticide market and industry, building on the information presented in the first two reports. It provides a review of the major national generic pesticide markets and a discussion of the various business strategies adopted by generic pesticide companies, both in terms of competing with each other and with the major R&D-based agrochemical companies. This section of the report also contains an in-depth analysis of the ways in which the major agrochemical companies try to maintain their market share after an ai has come off-patent, including finding ways to delay the manufacture of the ai by generic pesticide companies.

The report also explores the current and future forces driving the development of the generic pesticide industry. Such forces include: the consolidation of the agrochemical industry and the associated divestment of pesticide products and businesses; patent issues, especially data protection; ai re-registration initiatives in the EU and US, and the forced withdrawal of certain generic ais in these markets; and the efforts of industry associations.

In addition, the report contains three in-depth case studies on subjects of importance to the generic pesticide industry, such as product development, and two interviews with senior personnel within the generic pesticide industry, who provide a personal perspective on the issues raised in the report.

1.5 Information sources

A variety of sources of information have been utilised to produce the three reports. These include: the previous editions of the reports; the internet, especially the profiled companies’ web sites; stories that have appeared in Agrow; and other Agrow Reports. The author has also obtained a great deal of information and personal opinion from a large number of people working in the generic pesticide industry throughout the world.

In this way, the author has built up an accurate and detailed picture of the generic pesticide market and industry, and the challenges that it will face over the coming few years.

For the Products and Markets report, the author made use of chemical use data from the US Department of Agriculture’s National Agricultural Statistics Service, which provides information on the use of pesticides on the majority of US crop areas. For Europe, the author used pesticide use data published by EuroStat, although this was only available for groups of pesticides rather than for individual ais.

1.6 Introduction to Products and Markets report

This report contains details on the 100 most important generic pesticide ais in the world today. Total global sales were the main criteria for inclusion in the report, although this information was hard to obtain for some of the smaller ais. Nevertheless, all the major generic pesticide ais are detailed in this report, as well as a good representative selection of the smaller ais.

To decide on which of the smaller ais should be included, the author looked at how many were sold by a cross-section of the generic pesticide industry, and chose those that were manufactured by the most number of companies. Because many generic pesticide companies are now based in India or China, the smaller ais that are profiled tend to be skewed towards those that are sold by these companies, which means that there are a large number of pyrethroid and organophosphorus insecticides and rice herbicides. However, this does reflect the shifting focus of the generic pesticide industry towards Asian countries.

An ai is included in this report, and therefore classified as generic, if it is being independently manufactured by companies that did not originally develop the ai or have not obtained production licenses from the original developer. This means that certain newer ais have been included, such as imidiacloprid, even though they have not officially lost their patent-protection in certain markets. If an ai was being manufactured by a large number of generic producers, such as is happening with imidacloprid, then it was considered for inclusion.

Each profile contains general details on the ai and a list of the main manufacturers, including both generic (as detailed in the first report) and R&D-based companies. This is followed by information on regulatory status, market size and future prospects (see sections 1.7 and 1.8 for more details). The amount of information in each profile therefore mainly depends on how much regulatory scrutiny the ai is under and how much market data the author was able to obtain. Unsurprisingly, profiles for the bigger selling ais tend to contain more information than the profiles for the smaller ais.

1.7 Registration status

Many generic pesticide ais, especially the older ones, are coming under increasing regulatory scrutiny, and are having their registrations withdrawn or their use severely restricted in many countries. This is obviously having a major impact on sales.

Each profile therefore details the regulatory status of the ai in the major markets of Europe and the US. In both regions, the regulatory authorities are in the process of undertaking a wide-ranging review programme of existing ais, which, especially in Europe, has led to the withdrawal of the registrations for a number of ais. A profile may also contain an outline of the situation in other major markets where the ai is having its registration reviewed.

In Europe, the ongoing pesticide review programme was instigated in the early 1990s by the coming into force of the European Union (EU) pesticide registration directive (91/414/EEC). The main intention of this directive was to harmonise the registration of new pesticide ais at the EU level, but it also required that over 800 ais then being sold in pesticide products throughout Europe have their registrations renewed.

The European Commission decided to assess these ais in four groups. Details on the first group of 90 pesticides to be reviewed were published at the end of 1992. Companies wishing to support these ais through the review process were then required to provide the scientific information required by the Commission. This information was first assessed by one of the member state regulatory authorities, which then submitted a report on the ai to the Scientific Committee on Plant Health (SCPH; this role is now performed by the European Food Safety Authority). After reviewing the report, the SCPH made a recommendation to the European Commission’s Standing Committee on Plant Health (now the Standing Committee on the Food Chain and Animal Health) on whether or not the ai should be included in Annex 1 of the directive. A final decision on inclusion was then made by the Standing Committee.

Unfortunately, this review process took much longer than was originally envisaged. Although the process has sped up over the past few years, there are still a number of ais in the first list that haven’t received inclusion decisions and the whole review process will probably not now be finished until 2008.

In March 2000, the Commission published details of the three other groups of pesticide ais to be reviewed. The second group contained 148 ais, including 70 organophosphate and 22 carbamate insecticides, and the third group contained 388 ais. The fourth group contained a mixture of products, including biopesticides, natural extracts and attractants.

In November 2002, in an effort to speed up the process, the Commission published a list of 225 ais from the third group that would have their registrations withdrawn on July 2003, because no companies wished to support them through the review process. In January 2004, the Commission published a further list of 106 ais that it would withdraw from the market in March 2004, because no companies wished to support them.

In the US, pesticides are registered under the Federal Insecticide, Fungicide and Rodenticide Act (FIFRA), which was amended in 1988. This amendment instigated a programme requiring all ais registered before November 1984 to have their registrations reviewed. This applied to 1,150 ais in 45,000 formulated products, with the review programme to be carried out by the Office of Pesticide Programs, which is part of the US Environmental Protection Agency (EPA).

In 1996, the Food Quality Protection Act (FQPA) came into force; this widened the scope and considerations that needed to be applied regarding pesticide safety. As part of the FQPA, the EPA now had to assess the cumulative risks of certain pesticide groups with a common mechanism of toxicity, such as organophosphorous insecticides.

When the EPA completes the review and risk management decision for a pesticide that is subject to re-registration, it generally releases a Re-registration Eligibility Decision (RED). This summarises the risk assessment conclusions and outlines any risk reduction measures necessary for the pesticide to continue to be registered in the US. If the ai is also part of a group undergoing a cumulative assessment, the EPA releases an Interim Re-registration Eligibility Decision (IRED), which is upgraded to a RED on completion of the cumulative assessment.

1.8 Market profile

Each profile contains an estimate for the value of the global annual market for that ai. As there are no official figures for this kind of information, the estimates are necessarily rather broad. However, they should reflect the general size of the market, and should fairly accurately represent the range in market sizes for the 100 ais (see Table 1.3). It was especially difficult to obtain market information on the lowest-selling pesticides and so precise market sizes aren’t detailed below $50 million.

Table 1.3: Market value and sales prospects for top 100 pesticide ais <

Active ingredient

Activity

Market value ($m)

Sales prospects

glyphosate

Herbicide

$5,000

Rising

imidacloprid

Insecticide

$1,000

Rising

malathion

Insecticide

$400

Stable

paraquat

Herbicide

$400

Falling

acephate

Insecticide

$350

Rising

pendimethalin

Herbicide

$350

Stable

2,4-D

Herbicide

$325

Stable

acetochlor

Herbicide

$300

Rising

chlorpyrifos

Insecticide

$300

Falling

trifluralin

Herbicide

$300

Stable

atrazine

Herbicide

$280

Stable

imazethapyr

Herbicide

$280

Falling

lambda-cyhalothrin

Insecticide

$275

Rising

permethrin

Insecticide

$270

Falling

carbofuran

Insecticide

$250

Falling

deltamethrin

Insecticide

$250

Stable

mancozeb

Fungicide

$220

Rising

alpha-cypermethrin

Insecticide

$200

Rising

carbendazim

Fungicide

$200

Stable

chlorothalonil

Fungicide

$200

Stable

cypermethrin

Insecticide

$200

Rising

dichlorvos

Insecticide

$200

Falling

linuron

Herbicide

$200

Falling

methomyl

Insecticide

$200

Stable

monocrotophos

Insecticide

$200

Falling

tebuconazole

Fungicide

$200

Rising

abamectin

Insecticide

$180

Rising

metolachlor

Herbicide

$170

Falling

bifenthrin

Insecticide

$150

Rising

dicamba

Herbicide

$150

Stable

dimethoate

Insecticide

$150

Falling

isoproturon

Herbicide

$150

Stable

methamidophos

Insecticide

$150

Falling

propiconazole

Fungicide

$150

Falling

chlormequat chloride

Herbicide

$140

Stable

metribuzin

Herbicide

$140

Stable

bromoxynil

Herbicide

$130

Falling

endosulfan

Insecticide

$120

Falling

fluroxypyr

Herbicide

$120

Rising

propargite

Insecticide

$120

Stable

alachlor

Herbicide

$100

Falling

bensulfuron-methyl

Herbicide

$100

Rising

bentazone

Herbicide

$100

Stable

cyflurthin

Insecticide

$100

Rising

diclofop-methyl

Herbicide

$100

Stable

dicofol

Insecticide

$100

Stable

metamitron

Herbicide

$100

Stable

metsulfuron-methyl

Herbicide

$100

Rising

parathion-methyl

Insecticide

$100

Falling

prochloraz

Fungicide

$100

Rising

propanil

Herbicide

$100

Falling

pyrazosulfuron-ethyl

Herbicide

$100

Rising

quinalphos

Insecticide

$100

Stable

terbufos

Insecticide

$100

Falling

thiophanate-methyl

Fungicide

$100

Rising

trichlorfon

Insecticide

$100

Stable

buprofezin

Insecticide

$75

Rising

profenofos

Insecticide

$75

Falling

prometryn

Herbicide

$75

Falling

triadimefon

Fungicide

$70

Falling

benomyl

Fungicide

$60

Falling

ametryn

Herbicide

$50

Falling

amitraz

Insecticide

$50

Falling

butachlor

Herbicide

$50

Stable

cyhexatin

Insecticide

$50

Falling

cymoxanil

Fungicide

$50

Stable

diuron

Herbicide

$50

Stable

fenthion

Insecticide

$50

Falling

fluometuron

Herbicide

$50

Falling

ioxynil

Herbicide

$50

Falling

maneb

Fungicide

$50

Stable

MCPA

Herbicide

$50

Stable

molinate

Herbicide

$50

Falling

myclobutanil

Fungicide

$50

Rising

oxyfluorfen

Herbicide

$50

Stable

PCNB

Fungicide

$50

Falling

phorate

Insecticide

$50

Falling

phosphamidon

Insecticide

$50

Falling

simazine

Herbicide

$50

Falling

thiram

Fungicide

$50

Stable

acetamiprid

Insecticide

<$50

Stable

anilofos

Herbicide

<$50

Falling

captan

Fungicide

<$50

Falling

carbaryl

Insecticide

<$50

Falling

carbosulfan

Insecticide

<$50

Stable

chlorotoluron

Herbicide

<$50

Falling

chlorsulfuron

Herbicide

<$50

Rising

clomazone

Herbicide

<$50

Falling

copper oxychloride

Fungicide

<$50

Stable

diniconazole

Fungicide

<$50

Rising

ethion

Insecticide

<$50

Falling

fenvalerate

Insecticide

<$50

Falling

fosetyl-aluminium

Fungicide

<$50

Stable